This communication aims to present a cross-perspective – robotics, industrial engineering, sociology and ergonomics – research project experience dealing with development of collaborative robotics in SMEs. Our conviction is that Industry 4.0 must imply: (1) “departitioning” of disciplines involved in the design of work situations and (2) construction of hybrid approaches for understanding and transforming work. In this communication, we propose to relate such an experience on the basis of a research project – funded by the French National Agency for Research (ANR), and focused on transformation of French Small and Middle Companies (SMC’s) in relation to introduction of Collaborative Robotics. Collaborative Robotics is of particular interest for us as it embeds promises and pitfalls of articulation between technologies and work. However, these promises may be discussed and tempered by confronting them to actual design issues, work organization and transformation of work management.